⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27794702 | 0.91 | CPB2 (0.44) | — | |
| SCHEMBL27815868 | 0.91 | CPB2 (0.44) | — | |
| SCHEMBL13639464 | 0.91 | CPB2 (0.44) | — | |
| SCHEMBL5567339 | 0.85 | — | — | |
| SCHEMBL7888034 | 0.85 | THRB (0.40) | — | |
| SCHEMBL14646580 | 0.80 | — | — | |
| SCHEMBL249756 | 0.80 | — | — | |
| SCHEMBL3381571 | 0.78 | OPRM1 (0.44) | — | |
| SCHEMBL15209862 | 0.78 | — | — | |
| SCHEMBL18612864 | 0.77 | THRB (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240325573-A1 | X-RAY DEVELOPABLE MOLECULE, EMBOLISM MICROSPHERE AND PREPARATION METHODS THEREFOR | SHANGHAI HUIHE HEALTHCARE TECHNOLOGY CO., LTD. (CN) | 2024-10-03 | — | — | US | disclosed |
| WO-2023124736-A1 | X-RAY DEVELOPABLE MOLECULE, X-RAY DEVELOPABLE EMBOLIC MICROSPHERE AND PREPARATION METHOD THEREFOR | 上海汇禾医疗科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023124736-A1 | X-RAY DEVELOPABLE MOLECULE, X-RAY DEVELOPABLE EMBOLIC MICROSPHERE AND PREPARATION METHOD THEREFOR | 上海汇禾医疗科技有限公司 | 2023-07-06 | — | — | WO | disclosed |
| CN-114262279-B | X-ray developable molecule, embolism microsphere and preparation method thereof | 上海汇禾医疗科技有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-114262279-A | X-ray developable molecule, embolism microsphere and preparation method thereof | 上海汇禾医疗科技有限公司 | 2022-04-01 | — | — | CN | disclosed |
| US-20220008410-A1 | COMPOSITIONS OF CXCR4 INHIBITORS AND METHODS OF PREPARATION AND USE | X4 PHARMACEUTICALS, INC. | 2022-01-13 | — | — | US | disclosed |
| WO-2021028094-A1 | METHOD FOR THE DECOLORIZATION OF KERATIN MATERIAL THAT HAS BEEN DYED USING AN ORGANOSILICON COMPOUND AND A PIGMENT | HENKEL AG & CO. KGAA (DE) | 2021-02-18 | — | — | WO | disclosed |
| EP-2231711-B1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DE GMBH (DE) | 2012-11-07 | — | — | EP | disclosed |
| WO-2009077154-A1 | HYDROXYALKYL STARCH DERIVATIVES AND PROCESS FOR THEIR PREPARATION | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2009-06-25 | — | — | WO | disclosed |
| EP-2070950-A1 | Hydroxyalkyl starch derivatives and process for their preparation | Fresenius Kabi Deutschland GmbH (DE) | 2009-06-17 | — | — | EP | disclosed |