Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.59 |
| ▸ | CTSK | P43235 | 12/20 | 0.59 |
| ▸ | CTSB | P07858 | 11/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2526565 | 0.81 | CTSS (0.66) | CTSSCTSKCTSBCTSL | |
| SCHEMBL347013 | 0.74 | CTSS (1.00) | CTSSCTSKCTSBCTSL | |
| SCHEMBL8224461 | 0.65 | CTSS (0.72) | CTSSCTSKCTSBCTSL | |
| SCHEMBL2526563 | 0.64 | CTSS (0.59) | CTSSCTSKCTSBCTSL | |
| SCHEMBL2526560 | 0.64 | CTSS (0.59) | CTSSCTSKCTSBCTSL | |
| SCHEMBL23673632 | 0.63 | CTSS (0.49) | CTSSCTSKCTSBCTSL | |
| SCHEMBL31006852 | 0.63 | CTSS (0.60) | CTSSCTSKCTSBCTSL | |
| SCHEMBL8903133 | 0.62 | HSD11B1 (0.42) | CTSSCTSKCTSBHSD11B1 | |
| SCHEMBL8904921 | 0.62 | ALDH1A1 (0.46) | CTSSCTSKCTSBHSD11B1 | |
| Hydrochloric Acid SCHEMBL20335434 | 0.62 | CTSS (0.48) | CTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2520568-A1 | Spirocyclic nitriles as inhibitors of protease | SANOFI (FR) | 2012-11-07 | — | — | EP | disclosed |