Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.58 |
| ▸ | CTSB | P07858 | 17/20 | 0.58 |
| ▸ | CTSK | P43235 | 17/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346963 | 0.90 | CTSB (0.75) | CTSSCTSBCTSK | |
| SCHEMBL346070 | 0.86 | CTSB (0.69) | CTSSCTSBCTSK | |
| SCHEMBL8224236 | 0.84 | CTSS (0.76) | CTSSCTSBCTSKPOLB | |
| SCHEMBL347100 | 0.81 | CTSB (0.65) | CTSSCTSBCTSK | |
| SCHEMBL4070875 | 0.79 | CTSB (0.70) | CTSSCTSBCTSK | |
| SCHEMBL8226527 | 0.79 | CTSB (0.79) | CTSSCTSBCTSKPOLB | |
| SCHEMBL8223388 | 0.78 | CTSB (0.70) | CTSSCTSBCTSKPOLB | |
| SCHEMBL10238403 | 0.77 | CTSB (0.61) | CTSSCTSBCTSK | |
| SCHEMBL347060 | 0.77 | CTSB (0.59) | CTSSCTSBCTSK | |
| SCHEMBL12236970 | 0.77 | CTSB (0.49) | CTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2520568-A1 | Spirocyclic nitriles as inhibitors of protease | SANOFI (FR) | 2012-11-07 | — | — | EP | disclosed |