Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356967 | 0.82 | MAPT (0.48) | MAPTALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL7944445 | 0.76 | MAPT (0.46) | MAPTALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL28685256 | 0.72 | MAPT (0.44) | MAPTALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL11699661 | 0.72 | ALDH1A1 (0.45) | MAPTALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL26803231 | 0.70 | MAPT (0.43) | MAPTALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL8622333 | 0.70 | MAPT (0.48) | MAPTALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL28957585 | 0.70 | MAPT (0.43) | MAPTALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL25502829 | 0.69 | HDAC1 (0.46) | MAPTALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL27841531 | 0.69 | CYP1A2 (0.43) | MAPTALDH1A1GAAKDM4ETDP1 | |
| SCHEMBL29386059 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326645-B1 | COMPOUND WITH SEROTONINERGIC ACTIVITY, PROCESS FOR PREPARING IT AND PHARMACEUTICAL COMPOSITION COMPRISING IT | ACRAF (IT) | 2012-11-07 | — | — | EP | disclosed |