Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356967 | 0.73 | MAPT (0.48) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL13639779 | 0.70 | MAPT (0.46) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL8622333 | 0.70 | MAPT (0.48) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL11699661 | 0.68 | ALDH1A1 (0.45) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL6681437 | 0.68 | MAPT (0.42) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL28685256 | 0.68 | MAPT (0.44) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL2677107 | 0.68 | MAPT (0.71) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL1335991 | 0.68 | MAPT (0.56) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL24755747 | 0.67 | MAPT (0.41) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL31103542 | 0.66 | HDAC3 (0.51) | HDAC3HDAC1HDAC2MAPK1HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894516-B | Nitrogen-containing aryl dithiophene phenazine compound, and preparation method and application thereof | 黑龙江大学 | 2024-06-28 | — | — | CN | claimed |
| CN-115894516-A | Nitrogen-containing aryl dithiophene phenazine compound, and preparation method and application thereof | 黑龙江大学 | 2023-04-04 | — | — | CN | claimed |
| CN-115710280-A | Compound based on dithienophenazine receptor, synthetic method and application thereof | 黑龙江大学 | 2023-02-24 | — | — | CN | claimed |
| CN-115894516-B | Nitrogen-containing aryl dithiophene phenazine compound, and preparation method and application thereof | 黑龙江大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-115710280-B | Dithienophenazine receptor-based compounds, synthesis method and application thereof | 黑龙江大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-115894516-A | Nitrogen-containing aryl dithiophene phenazine compound, and preparation method and application thereof | 黑龙江大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-115710280-A | Compound based on dithienophenazine receptor, synthetic method and application thereof | 黑龙江大学 | 2023-02-24 | — | — | CN | disclosed |