Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28072152 | 0.74 | MAPT (0.39) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL2356967 | 0.73 | MAPT (0.48) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL10978305 | 0.71 | ALDH1A1 (0.52) | MAPTKDM4EGAAALDH1A1KMT2A | |
| SCHEMBL8622331 | 0.70 | MAPT (0.52) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL13639779 | 0.70 | MAPT (0.46) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL28957585 | 0.70 | MAPT (0.43) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL26803231 | 0.70 | MAPT (0.43) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL251644 | 0.69 | ALDH1A1 (0.43) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3977426 | 0.68 | MAPT (0.68) | MAPTKDM4EGAAALDH1A1MEN1 | |
| SCHEMBL11699661 | 0.68 | ALDH1A1 (0.45) | MAPTKDM4EGAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10045690-A | — | — | None | — | — | JP | disclosed |
| JP-H1045690-A | BIS-SUBSTITUTED PHENOXYPHENYLENEDIAMINE DERIVATIVE AND PRODUCTION THEREOF | NISSAN CHEM IND LTD | 1998-02-17 | — | — | JP | disclosed |