Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443193 | 0.87 | TSHR (0.46) | TSHRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8525124 | 0.84 | VCAM1 (0.53) | TSHRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL27573659 | 0.78 | HSD17B10 (0.53) | TSHRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL29450699 | 0.77 | MEN1 (0.65) | TSHRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL29903883 | 0.77 | MEN1 (0.65) | TSHRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8623371 | 0.77 | MEN1 (0.65) | TSHRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL187061 | 0.76 | ALDH1A1 (0.63) | TSHRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8686458 | 0.75 | ALDH1A1 (0.52) | TSHRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL4958995 | 0.75 | TSHR (0.52) | TSHRLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL29715190 | 0.75 | TSHR (0.50) | TSHRLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2520557-A1 | Novel precursors of glutamate derivatives | Bayer Pharma Aktiengesellschaft (DE) | 2012-11-07 | — | — | EP | disclosed |