SCHEMBL1364019

SCHEMBL1364019

CCCOC(=O)CCCCBr

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.63
DNM1 Q05193 1/20 0.52
PAM P19021 2/20 0.47
PRSS1 P07477 1/20 0.45
PRSS2 P07478 1/20 0.45
PRSS3 P35030 1/20 0.45
ALDH1A1 P00352 3/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TSHR P16473 2/20 0.44
MAPT P10636 2/20 0.44
EPHX2 P34913 1/20 0.43
FAAH O00519 1/20 0.43
MAPK1 P28482 1/20 0.43
LMNA P02545 1/20 0.43
CYP3A4 P08684 1/20 0.43
ATM Q13315 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
USP2 O75604 1/20 0.42
NAAA Q02083 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1364732 0.98 DGKA (0.67) DGKADNM1PAMPRSS1PRSS2
SCHEMBL1369366 0.98 DGKA (0.67) DGKADNM1PAMPRSS1PRSS2
SCHEMBL1366436 0.98 DGKA (0.67) DGKADNM1PAMPRSS1PRSS2
SCHEMBL1366442 0.98 DGKA (0.67) DGKADNM1PAMPRSS1PRSS2
SCHEMBL1364372 0.93 DGKA (0.59) DGKADNM1PAMPRSS1PRSS2
SCHEMBL33810 0.91 DGKA (0.74) DGKADNM1PAMPRSS1PRSS2
SCHEMBL1365023 0.89 DGKA (0.67) DGKADNM1PAMPRSS1PRSS2
SCHEMBL495220 0.89 DGKA (0.78) DGKADNM1PAMPRSS1PRSS2
SCHEMBL494731 0.89 DGKA (0.78) DGKADNM1PAMPRSS1PRSS2
SCHEMBL494910 0.89 DGKA (0.78) DGKADNM1PAMPRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11958802-B2 Migration-resistant photopolymerization sensitizer KAWASAKI KASEI CHEMICALS LTD. (JP) 2024-04-16 US disclosed
US-20220106254-A1 MIGRATION-RESISTANT PHOTOPOLYMERIZATION SENSITIZER KAWASAKI KASEI CHEMICALS LTD. (JP) 2022-04-07 US disclosed
CN-113166036-A Photopolymerisable sensitizers having migration resistance 川崎化成工业株式会社 2021-07-23 CN disclosed
WO-2020209209-A1 RADICAL PHOTOCURING OXYGEN INHIBITION REDUCER, RADICAL PHOTOPOLYMERIZABLE COMPOSITION CONTAINING RADICAL PHOTOCURING OXYGEN INHIBITION REDUCER, COATING CONTAINING RADICAL PHOTOCURING OXYGEN INHIBITION REDUCER, AND METHOD FOR CURING SAME 川崎化成工業株式会社 2020-10-15 WO disclosed
WO-2020121384-A1 PHOTOPOLYMERIZATION SENSITIZER HAVING MIGRATION RESISTANCE 川崎化成工業株式会社 2020-06-18 WO disclosed
WO-2020054874-A1 PHOTOPOLYMERIZATION SENSITIZER 川崎化成工業株式会社 2020-03-19 WO disclosed
WO-2020054116-A1 PHOTOPOLYMERIZATION SENSITIZER 川崎化成工業株式会社 2020-03-19 WO disclosed
CN-104837810-B Chloramines ketone derivatives 奥克兰服务有限公司 2019-08-06 CN disclosed
US-20190169113-A1 Ketamine Derivatives AUCKLAND UNISERVICES LTD (NZ) 2019-06-06 US disclosed
US-10239825-B2 Ketamine derivatives AUCKLAND UNISERVICES LIMITED (NZ) 2019-03-26 US disclosed
EP-1758948-A2 POLYHYDROXYALKANOIC ACID HAVING VINYL, ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR Canon Kabushiki Kaisha (JP) 2007-03-07 EP disclosed
US-20060194071-A1 Developer carrying member and development apparatus CANON KABUSHIKI KAISHA (JP) 2006-08-31 US disclosed
US-20050287484-A1 Resin-coated carrier for electrophotographic developer CANON KABUSHIKI KAISHA (JP) 2005-12-29 US disclosed
WO-2005121204-A2 POLYHYDROXYALKANOIC ACID HAVING VINYL, ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121904-A1 CHARGE CONTROL AGENT, TONER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121205-A2 POLYHYDROXYALKANOATE HAVING ESTER GROUP, CABOXYL GROUP, AND SULFONIC GROUP, AND METHOD OF PRODUCING THE SAME CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
WO-2005121208-A1 POLYHYDROXYALKANOIC ACID HAVING ESTER, CARBOXYL OR SULFONIC ACID GROUP AND PRODUCING METHOD THEREFOR CANON KABUSHIKI KAISHA (JP) 2005-12-22 WO disclosed
US-4313947-A TREATMENT OF BLOOD DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1982-02-02 US disclosed
US-4216220-A Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1980-08-05 US disclosed
US-4070470-A BENCYCLOAMIDE DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JA) 1978-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10239825-B2 Ketamine derivatives OPRK1, KCNK5, OPRL1 DGKA 1595/4885DNM1 3584/4885PAM 2632/4885
US-20190169113-A1 Ketamine Derivatives OPRK1, KCNK5, KCNQ5 DGKA 1500/4885DNM1 3572/4885PAM 1485/4885
US-11958802-B2 Migration-resistant photopolymerization sensitizer F12, F10, PCNA DGKA 2032/4885DNM1 4250/4885PAM 956/4885
US-20220106254-A1 MIGRATION-RESISTANT PHOTOPOLYMERIZATION SENSITIZER F12, F10, PCNA DGKA 2032/4885DNM1 4250/4885PAM 956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.