SCHEMBL13640265

SCHEMBL13640265

CCCCC(CC)Cn1c2ccc(C(=O)c3cccc(C)c3)cc2c2cc(C(=O)c3cccc(OC)c3)ccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 5/20 0.44
MTNR1B P49286 1/20 0.44
MAPT P10636 3/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
HCRTR1 O43613 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ELANE P08246 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1980186 0.95 CNR2 (0.47) CNR2MTNR1BMAPTKDM4EMEN1
SCHEMBL25515583 0.83 CNR2 (0.56) CNR2MAPTKDM4ENPC1HCRTR1
SCHEMBL1978626 0.83 CNR2 (0.62) CNR2KDM4ENPC1ALDH1A1LMNA
SCHEMBL24494686 0.82 CNR2 (0.61) CNR2KDM4ENPC1ALDH1A1HPGD
SCHEMBL1978510 0.80 CNR2 (0.68) CNR2KDM4ENPC1ALDH1A1HPGD
SCHEMBL13640281 0.78 CNR2 (0.56) CNR2KDM4ENPC1ALDH1A1LMNA
SCHEMBL1978488 0.78 CNR2 (0.52) CNR2MAPTKDM4ENPC1ALDH1A1
SCHEMBL13320185 0.78 KDM4E (0.43) CNR2MAPTKDM4EMEN1NPC1
SCHEMBL22828459 0.77 CNR2 (0.47) CNR2KDM4ENPC1ALDH1A1LMNA
SCHEMBL23801802 0.77 ALDH1A1 (0.45) CNR2KDM4ENPC1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8569393-B2 UV-LED curable compositions and inks AGFA-GEVAERT N.V. (BE) 2013-10-29 US disclosed
US-20120283349-A1 UV-LED CURABLE COMPOSITIONS AND INKS AGFA-GEVAERT N.V. (BE) 2012-11-08 US disclosed