SCHEMBL1364036

SCHEMBL1364036

C[CH]NC(CCC)CCC

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3376456 0.89
SCHEMBL8374759 0.79 ADH1B (0.47)
SCHEMBL8374807 0.79 ADH1B (0.47)
SCHEMBL22157413 0.78 TAS1R3 (0.32) TAS1R3TAS1R1
SCHEMBL22157416 0.78 TAS1R3 (0.32) TAS1R3TAS1R1
SCHEMBL1678821 0.75
SCHEMBL22157365 0.74 TAS1R3 (0.35) TAS1R3TAS1R1
SCHEMBL8627522 0.74 ADH1B (0.46) TAS1R3TAS1R1
SCHEMBL3373342 0.74 TAS1R3 (0.38) TAS1R3TAS1R1
SCHEMBL543188 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110945438-B Toner for developing electrostatic image 日本瑞翁株式会社 2023-09-29 CN disclosed
CN-108780288-B Positively chargeable black toner 日本瑞翁株式会社 2022-03-01 CN disclosed
US-20200166859-A1 TONER FOR DEVELOPING ELECTROSTATIC IMAGES ZEON CORPORATION (JP) 2020-05-28 US disclosed
CN-110945438-A Toner for developing electrostatic image 日本瑞翁株式会社 2020-03-31 CN disclosed
US-20190041764-A1 POSITIVELY-CHARGEABLE BLACK TONER ZEON CORPORATION (JP) 2019-02-07 US disclosed
US-8067140-B2 reduced residual amount of a decomposed product of a polymerization initiator and an unreacted polymerizable monomer (mainly styrene), less odor produced upon fixing so as to avoid deteriorating surrounding environment, an excellent shelf stability at high temperature upon storing or anti-blocking ZEON CORPORATION (JP) 2011-11-29 US disclosed
US-20100324091-A1 Pyrazolone Derivative KOWA COMPANY, LTD. (JP) 2010-12-23 US disclosed
EP-2172458-A1 PYRAZOLONE DERIVATIVE Kowa Company, Ltd. (JP) 2010-04-07 EP disclosed
US-20080182189-A1 reduced residual amount of a decomposed product of a polymerization initiator and an unreacted polymerizable monomer (mainly styrene), less odor produced upon fixing so as to avoid deteriorating surrounding environment, an excellent shelf stability at high temperature upon storing or anti-blocking ZEON CORPORATION (JP) 2008-07-31 US disclosed
EP-1844052-A1 THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION Pharmacia & Upjohn Company LLC (US) 2007-10-17 EP disclosed
WO-2006079916-A1 THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION PHARMACIA & UPJOHN COMPANY LLC (US) 2006-08-03 WO disclosed
EP-0870765-B1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARM CO LTD (JP) 2003-11-19 EP disclosed
US-5981557-A HAVING IMPROVING EFFECTS ON THE DYSMOTILITY IN THE GASTROINTESTINAL TRACT ZERIA PHARMACEUTICAL CO., LTD. (JP) 1999-11-09 US disclosed
EP-0870765-A1 AMINOTHIAZOLE DERIVATIVES, DRUG CONTAINING THE SAME AND INTERMEDIATE IN THE PRODUCTION OF THE COMPOUNDS ZERIA PHARMACEUTICAL CO., LTD. (JP) 1998-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100324091-A1 Pyrazolone Derivative SERPINE1, SERPINC1, TFPI TAS1R3 1059/4885TAS1R1 745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.