Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HPGDS | O60760 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2326371 | 0.88 | HPGDS (0.54) | NPC1RAB9AHPGDSCTSBCTSS | |
| SCHEMBL2326366 | 0.88 | HPGDS (0.54) | NPC1RAB9AHPGDSCTSBCTSS | |
| SCHEMBL13640417 | 0.85 | SMN1; SMN2 (0.53) | NPC1RAB9ACTSBCTSSCTSK | |
| SCHEMBL18803705 | 0.83 | NPC1 (0.59) | NPC1RAB9AHPGDSCTSBCTSS | |
| SCHEMBL18803706 | 0.83 | CA2 (0.43) | — | |
| SCHEMBL2328024 | 0.80 | CA2 (0.52) | CTSBCTSS | |
| SCHEMBL2328019 | 0.80 | CA2 (0.52) | CTSBCTSS | |
| SCHEMBL27822898 | 0.78 | GAA (0.51) | RAB9ACTSBCTSSCTSKL3MBTL1 | |
| SCHEMBL2330340 | 0.78 | GAA (0.51) | RAB9ACTSBCTSSCTSKL3MBTL1 | |
| SCHEMBL13640416 | 0.78 | TAS1R3 (0.53) | CTSBCTSSCTSKL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170119638-A1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2017-05-04 | — | — | US | disclosed |
| US-9066914-B2 | Prophylactic or ameliorating agent for pigmentation | POLA CHEMICAL INDUSTRIES INC. (JP) | 2015-06-30 | — | — | US | disclosed |
| US-20120282203-A1 | PROPHYLACTIC OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2012-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119638-A1 | MELANOGENESIS INHIBITOR COMPRISING D-PANTOTHENYL ALCOHOL, AND SKIN-WHITENING COSMETIC CONTAINING SAME MELANOGENESIS INHIBITOR | MC1R, TYR, NAMPT | NPC1 2716/4885RAB9A 3168/4885HPGDS 1082/4885 |
| US-20120282203-A1 | PROPHYLACTIC OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, NQO1 | NPC1 762/4885RAB9A 2440/4885HPGDS 768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.