SCHEMBL13640838

SCHEMBL13640838

O=C1c2c(Cl)ccc(Cl)c2C(=O)c2c(F)c(F)c(F)c(F)c21

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.41
CES1 P23141 4/20 0.40
THRB P10828 1/20 0.31
NSD2 O96028 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9059735 0.88 CSNK2A2 (0.44) ADORA2ACES1THRB
SCHEMBL1477149 0.84 CES1 (0.50) ADORA2ACES1THRBNSD2
SCHEMBL8369799 0.78 CA1 (0.35) THRB
SCHEMBL5872482 0.74 GRIN2D (0.33)
SCHEMBL26328324 0.73 CES2 (0.47) CES1NSD2
SCHEMBL7913484 0.73 MAPT (0.48) ADORA2ACES1THRBNSD2
SCHEMBL6674009 0.70 CSNK2A2 (0.44) ADORA2ATHRB
SCHEMBL10355771 0.70 ADORA2A (0.73) ADORA2ACES1THRB
SCHEMBL7742020 0.70 CSNK2A2 (0.54) ADORA2ACES1THRBNSD2
SCHEMBL10356104 0.70 ADORA2A (0.73) ADORA2ACES1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9244034-B2 Electrochemical pH measurement SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2016-01-26 US disclosed
US-9244034-B2 Electrochemical pH measurement SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2016-01-26 US disclosed
US-20120279874-A1 ELECTROCHEMICAL PH MEASUREMENT SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2012-11-08 US disclosed
US-20120279874-A1 ELECTROCHEMICAL PH MEASUREMENT SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2012-11-08 US disclosed