Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.32 |
| ▸ | RGS4 | P49798 | 2/20 | 0.32 |
| ▸ | RGS8 | P57771 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 5/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.30 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1364141 | 0.88 | SMN1; SMN2 (0.32) | SMN1; SMN2L3MBTL1 | |
| SCHEMBL1362015 | 0.79 | AKR1B1 (0.33) | — | |
| SCHEMBL1362827 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2GAATP53TDP1ABL1 | |
| SCHEMBL1363355 | 0.72 | GAA (0.36) | GAATP53TDP1ABL1RIN1 | |
| SCHEMBL11535351 | 0.72 | MGLL (0.36) | SMN1; SMN2GAATP53HPGDCNR1 | |
| SCHEMBL1364225 | 0.71 | PIK3CD (0.34) | KMT2A | |
| SCHEMBL4621192 | 0.71 | PIK3CD (0.34) | KMT2A | |
| SCHEMBL4620897 | 0.69 | SMN1; SMN2 (0.35) | SMN1; SMN2RGS4RGS8 | |
| SCHEMBL11681731 | 0.69 | GAA (0.34) | SMN1; SMN2GAATP53TDP1ABL1 | |
| SCHEMBL1363415 | 0.69 | TP53 (0.34) | SMN1; SMN2GAATP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8066977-B2 | Agent for permanent hair waving containing heterocyclic mercapto compound | SHOWA DENKO K.K. (JP) | 2011-11-29 | — | — | US | disclosed |
| EP-1883454-B1 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | SHOWA DENKO KK (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-20090208439-A1 | Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound | SHOWA DENKO K.K. (JP) | 2009-08-20 | — | — | US | disclosed |
| EP-1883454-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | Showa Denko K.K. (JP) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006126729-A2 | AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND | SHOWA DENKO K.K. (JP) | 2006-11-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208439-A1 | Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound | NSD3, WNT3, MSRB3 | SMN1; SMN2 3473/4885GAA 4854/4885TP53 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.