SCHEMBL13643291

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13642920	0.91	DHODH (0.46)	ALDH1A1DHODHL3MBTL1CCR1CCR8
	SCHEMBL13083943	0.85	CYP11B1 (0.44)	ALDH1A1DHODHCYP11B1METAP1MAPK1
	SCHEMBL13083964	0.85	CYP11B1 (0.44)	ALDH1A1DHODHCYP11B1METAP1MAPK1
	SCHEMBL13643280	0.82	ALDH1A1 (0.42)	ALDH1A1L3MBTL1CCR1CCR8CYP11B1
	SCHEMBL13643281	0.81	NPC1 (0.43)	ALDH1A1L3MBTL1CYP11B1HSD17B10NPC1
	SCHEMBL13643290	0.81	ALDH1A1 (0.43)	ALDH1A1DHODHL3MBTL1CCR1CCR8
	SCHEMBL13643285	0.81	KDM4E (0.38)	ALDH1A1DHODHL3MBTL1CYP11B1MAPK1
	SCHEMBL13643023	0.79	MAPK1 (0.47)	ALDH1A1DHODHL3MBTL1CCR1CCR8
	SCHEMBL9974938	0.78	DHODH (0.46)	ALDH1A1DHODHL3MBTL1CCR1CCR8
	SCHEMBL13642984	0.78	DHODH (0.46)	DHODHL3MBTL1CCR1CCR8METAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.