SCHEMBL13643285

SCHEMBL13643285

Clc1cc(-c2ccc(-c3nc4ccccc4c4ccccc34)cc2)nc2c1cc(-c1cc3ccccc3c3ccccc13)c1ccccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
ALDH1A1 P00352 3/20 0.36
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
ESRRB O95718 1/20 0.36
ESRRA P11474 1/20 0.36
THRB P10828 1/20 0.36
PKM P14618 1/20 0.36
CYP11B1 P15538 1/20 0.35
ADORA1 P30542 1/20 0.35
ACACA Q13085 1/20 0.34
ACHE P22303 1/20 0.34
DHODH Q02127 3/20 0.34
ALOX5 P09917 1/20 0.33
ACP1 P24666 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13642919 0.91 CYP11B1 (0.39) KDM4EL3MBTL1LMNAGAAALDH1A1
SCHEMBL13643281 0.84 NPC1 (0.43) KDM4EL3MBTL1LMNAGAAALDH1A1
SCHEMBL13083866 0.84 CYP11B1 (0.40) KDM4EL3MBTL1LMNAGAAALDH1A1
SCHEMBL13642715 0.84 CYP11B1 (0.40) KDM4EL3MBTL1LMNAGAAALDH1A1
SCHEMBL13643021 0.81 MEN1 (0.39) KDM4EL3MBTL1LMNAALDH1A1ACACA
SCHEMBL13642855 0.81 ACACA (0.49) KDM4EL3MBTL1LMNAALDH1A1ACACA
SCHEMBL13642994 0.81 ACACA (0.49) KDM4EL3MBTL1LMNAALDH1A1ACACA
SCHEMBL13643178 0.81 ACACA (0.49) KDM4EL3MBTL1LMNAALDH1A1ACACA
SCHEMBL13643291 0.81 ALDH1A1 (0.43) KDM4EL3MBTL1LMNAALDH1A1PKM
SCHEMBL13643280 0.80 ALDH1A1 (0.42) L3MBTL1LMNAALDH1A1CYP11B1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8796917-B2 Compound for an organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode CHEIL INDUSTRIES, INC (KR) 2014-08-05 US disclosed
US-8796917-B2 Compound for an organic optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode CHEIL INDUSTRIES, INC (KR) 2014-08-05 US disclosed
US-20120280613-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-11-08 US disclosed
US-20120280613-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2012-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120280613-A1 COMPOUND FOR AN ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME, AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE OR51E2, AOX1, OR10J3 KDM4E 3229/4885L3MBTL1 1339/4885LMNA 4732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.