Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835296 | 0.90 | ALDH1A1 (0.41) | ALDH1A1LMNARAB9APOLBTP53 | |
| SCHEMBL2473833 | 0.89 | HDAC1 (0.50) | ALDH1A1LMNARAB9APOLBTP53 | |
| SCHEMBL13646206 | 0.88 | ALDH1A1 (0.40) | ALDH1A1LMNAPOLBTP53MEN1 | |
| SCHEMBL13646199 | 0.81 | ALDH1A1 (0.52) | ALDH1A1LMNARAB9APOLBTP53 | |
| SCHEMBL13646239 | 0.81 | KDM4E (0.47) | ALDH1A1LMNARAB9APOLBTP53 | |
| SCHEMBL13646250 | 0.80 | ALDH1A1 (0.51) | ALDH1A1LMNARAB9APOLBTP53 | |
| SCHEMBL4388358 | 0.78 | ALDH1A1 (0.42) | ALDH1A1LMNAPOLBTP53MEN1 | |
| SCHEMBL2473804 | 0.77 | HDAC1 (0.43) | ALDH1A1LMNAPOLBMEN1KMT2A | |
| SCHEMBL3832445 | 0.77 | ACKR3 (0.47) | ALDH1A1LMNARAB9APOLBTP53 | |
| SCHEMBL2475880 | 0.77 | LTA4H (0.44) | ALDH1A1LMNAPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |