Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12051694 | 0.90 | CD274 (0.41) | LMNATSHRHDAC1HDAC6RAB9A | |
| SCHEMBL2479745 | 0.88 | HDAC1 (0.46) | LMNATSHRHDAC1HDAC6RAB9A | |
| SCHEMBL13646301 | 0.81 | MAPT (0.53) | LMNATSHRMAPTALDH1A1POLB | |
| SCHEMBL3836028 | 0.80 | RAB9A (0.49) | LMNATSHRHDAC1HDAC6RAB9A | |
| SCHEMBL13646199 | 0.79 | ALDH1A1 (0.52) | LMNATSHRRAB9AMAPTALDH1A1 | |
| SCHEMBL3836365 | 0.79 | HDAC1 (0.54) | LMNAHDAC1HDAC6RAB9AMAPT | |
| SCHEMBL13646306 | 0.78 | HSD17B10 (0.47) | LMNATSHRMAPTALDH1A1TP53 | |
| SCHEMBL3835148 | 0.78 | HDAC1 (0.47) | TSHRHDAC1HDAC6RAB9AMAPT | |
| SCHEMBL12051689 | 0.78 | CD274 (0.44) | LMNATSHRHDAC1HDAC6RAB9A | |
| SCHEMBL13646250 | 0.78 | ALDH1A1 (0.51) | LMNATSHRRAB9AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |