SCHEMBL2479745

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3836365	0.90	HDAC1 (0.54)	HDAC1HDAC3HDAC2HDAC4HDAC7
	SCHEMBL13646231	0.88	LMNA (0.40)	HDAC1HDAC6LMNATSHRRAB9A
	SCHEMBL12051694	0.88	CD274 (0.41)	HDAC1HDAC6LMNATSHRKDM1A
	SCHEMBL3835148	0.88	HDAC1 (0.47)	HDAC1HDAC3HDAC2HDAC4HDAC7
	SCHEMBL2474808	0.87	ALDH1A1 (0.54)	HDAC1HDAC3HDAC2HDAC4HDAC7
	SCHEMBL2476586	0.86	HSD17B10 (0.55)	HDAC1HDAC3HDAC2HDAC4HDAC7
	SCHEMBL2473980	0.79	ALDH1A1 (0.54)	HDAC1LMNATSHRALDH1A1TP53
	SCHEMBL2473792	0.79	ALDH1A1 (0.54)	HDAC1LMNATSHRALDH1A1POLB
	SCHEMBL2474354	0.79	MAPT (0.57)	HDAC1LMNATSHRALDH1A1POLB
	SCHEMBL2475895	0.79	MCHR1 (0.55)	HDAC1LMNATSHRALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.