Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397087 | 0.88 | HDAC1 (0.48) | HDAC1HDAC6ALDH1A1HPGDMAPT | |
| SCHEMBL12052038 | 0.86 | HDAC1 (0.50) | HDAC1HDAC6ALDH1A1HPGDMAPT | |
| SCHEMBL13646294 | 0.79 | HDAC1 (0.51) | HDAC1HDAC6KDM4EHDAC3HDAC2 | |
| SCHEMBL13646269 | 0.78 | HDAC1 (0.51) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL12199930 | 0.77 | HDAC1 (0.52) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL13646307 | 0.72 | HSD17B10 (0.48) | HDAC1HDAC6ALDH1A1HPGDMAPT | |
| SCHEMBL12199822 | 0.72 | HDAC6 (0.46) | HDAC1HDAC6ALDH1A1KDM4EHDAC3 | |
| SCHEMBL12199753 | 0.71 | HTT (0.47) | HDAC1HDAC6ALDH1A1MAPTRECQL | |
| SCHEMBL13646279 | 0.71 | NAMPT (0.48) | HDAC1HDAC6ALDH1A1KDM4ETSHR | |
| SCHEMBL13646237 | 0.71 | POLB (0.49) | HDAC1HDAC6ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |