Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2502242 | 0.87 | HDAC6 (0.45) | HDAC6HDAC1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL4399806 | 0.86 | HDAC1 (0.52) | HDAC6HDAC1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL13646294 | 0.77 | HDAC1 (0.51) | HDAC6HDAC1KDM4EMEN1KMT2A | |
| SCHEMBL13646319 | 0.76 | ALDH1A1 (0.44) | HDAC6HDAC1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL13646269 | 0.76 | HDAC1 (0.51) | HDAC6HDAC1KMT2AROCK1TSHR | |
| SCHEMBL13646243 | 0.72 | HDAC1 (0.49) | HDAC6HDAC1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL2474631 | 0.71 | HDAC1 (0.50) | HDAC6HDAC1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL7300382 | 0.71 | L3MBTL1 (0.67) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL9615978 | 0.70 | ALDH1A1 (0.64) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL3832767 | 0.70 | HDAC1 (0.54) | HDAC6HDAC1ALDH1A1ROCK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-B1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2011-10-12 | — | — | EP | disclosed |