Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 16/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2478129 | 0.87 | HDAC1 (0.50) | HDAC1HDAC6GAAHDAC3HDAC2 | |
| SCHEMBL3834376 | 0.86 | GAA (0.54) | HDAC1HDAC6GAAHDAC3HDAC2 | |
| SCHEMBL2476409 | 0.82 | HDAC1 (0.43) | HDAC1HDAC6GAAHDAC3HDAC2 | |
| SCHEMBL3834422 | 0.80 | HDAC1 (0.54) | HDAC1HDAC6GAAHDAC3HDAC2 | |
| SCHEMBL13646269 | 0.80 | HDAC1 (0.51) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL13646243 | 0.79 | HDAC1 (0.49) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL12199822 | 0.77 | HDAC6 (0.46) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL3837721 | 0.76 | HDAC1 (0.42) | HDAC1HDAC6GAAHDAC3HDAC2 | |
| SCHEMBL4396435 | 0.76 | HDAC1 (0.49) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL12199930 | 0.75 | HDAC1 (0.52) | HDAC1HDAC6HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |