Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 12/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13651762 | 0.84 | DRD4 (0.60) | DRD4DRD2ALDH1A1GLA | |
| SCHEMBL11591604 | 0.84 | DRD4 (0.60) | DRD4DRD2ALDH1A1GLA | |
| SCHEMBL11592157 | 0.83 | DRD4 (0.61) | DRD4DRD2ALDH1A1GLASLC6A4 | |
| SCHEMBL1044588 | 0.83 | ALDH1A1 (0.46) | DRD4DRD2ALDH1A1GLATP53 | |
| SCHEMBL4177996 | 0.83 | ALDH1A1 (0.46) | DRD4DRD2ALDH1A1GLATP53 | |
| SCHEMBL3354399 | 0.83 | ALDH1A1 (0.46) | DRD4DRD2ALDH1A1GLATP53 | |
| SCHEMBL7962015 | 0.82 | ALDH1A1 (0.49) | DRD4DRD2ALDH1A1GLATP53 | |
| SCHEMBL29847389 | 0.82 | ALDH1A1 (0.49) | DRD4DRD2ALDH1A1GLATP53 | |
| SCHEMBL7962011 | 0.82 | ALDH1A1 (0.49) | DRD4DRD2ALDH1A1GLATP53 | |
| SCHEMBL2338368 | 0.82 | ALDH1A1 (0.49) | DRD4DRD2ALDH1A1GLATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120192-A2 | PROCESS FOR THE PREPARATION OF BENZO-FUSED HETEROARYL DERIVATIVES | JASSEN PHARMACEUTICA, N.V. (BE) | 2009-10-01 | — | — | WO | disclosed |