Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962011 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL7962015 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL29847389 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL2230996 | 0.89 | TTR (0.45) | ALDH1A1GLATSHRTP53CYP3A4 | |
| SCHEMBL30161198 | 0.89 | TTR (0.45) | ALDH1A1GLATSHRTP53CYP3A4 | |
| SCHEMBL9840397 | 0.87 | KDM4E (0.44) | ALDH1A1GLATDP1TSHRSMN1; SMN2 | |
| SCHEMBL2337120 | 0.86 | ALDH1A1 (0.49) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL9803136 | 0.85 | ALDH1A1 (0.59) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL2122103 | 0.83 | ALDH1A1 (0.46) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL4294711 | 0.83 | ALDH1A1 (0.46) | ALDH1A1GLATDP1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308328-B1 | (BENZYL-PIPERIDINO)-1-PROPANOL-2 DERIVATIVES, THEIR PREPARATION, THEIR USE AS MICROBICIDES AND COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1991-12-04 | — | — | EP | claimed |
| EP-0086256-B1 | 1-(2,4-DICHLOROPHENOXY)-3-(3,4-DIMETHOXY-BETA-PHENETHYLAMINO)-PROPAN-2-0L, PROCESSES FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | VEB Arzneimittelwerk Dresden (DD) | 1985-08-21 | — | — | EP | claimed |
| EP-0086256-A1 | 1-(2,4-Dichlorophenoxy)-3-(3,4-dimethoxy-beta-phenethylamino)-propan-2-0l, processes for its preparation and pharmaceutical compositions containing it | VEB Arzneimittelwerk Dresden (DD) | 1983-08-24 | — | — | EP | claimed |
| US-4246189-A | FOR EASE OF MATERIALS HANDLING | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-01-20 | — | — | US | claimed |
| US-20240166602-A1 | SUBSTITUTED DIARYL COMPOUND AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF | SHANDONG FIRST MEDICAL UNIV & SHANDONG ACADEMY OF MEDICAL SCIENCES (CN) | 2024-05-23 | — | — | US | disclosed |
| WO-2022262350-A1 | SUBSTITUTED DIARYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 山东第一医科大学(山东省医学科学院) | 2022-12-22 | — | — | WO | disclosed |
| US-20190092727-A1 | Piperidine Compounds, Pharmaceutical Composition Comprising The Same And Its Use | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2019-03-28 | — | — | US | disclosed |
| US-10144709-B2 | Piperidine compounds, pharmaceutical composition comprising the same and its use | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2018-12-04 | — | — | US | disclosed |
| CN-105646331-B | Piperidine compounds, the medical composition and its use containing the compound | 爱思开生物制药株式会社 | 2018-07-03 | — | — | CN | disclosed |
| US-20170275250-A1 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | SK BIOPHARMACEUTICALS CO LTD (KR) | 2017-09-28 | — | — | US | disclosed |
| US-9676718-B2 | Piperidine compounds, pharmaceutical composition comprising the same and its use | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2017-06-13 | — | — | US | disclosed |
| US-9593102-B2 | Piperidine compounds, pharmaceutical composition comprising the same and its use | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2017-03-14 | — | — | US | disclosed |
| US-4269838-A | ADRENERGIC BLOCKING AGENTS; ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS | NIPPON SHINYAKU CO. LTD. (JP) | 1981-05-26 | — | — | US | disclosed |
| US-4256756-A | ADRENERGIC BLOCKING AGENTS, ANTIDEPRESSANTS | BOEHRINGER INGELHEIM GMBH (DE) | 1981-03-17 | — | — | US | disclosed |
| US-4255430-A | ANDRENERGIC RECEPTOR BLOCKING AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1981-03-10 | — | — | US | disclosed |
| US-4246189-A | FOR EASE OF MATERIALS HANDLING | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-01-20 | — | — | US | disclosed |
| US-4212877-A | ANTIDEPRESSANTS, ADRENERGIC BLOCKING AGENTS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-07-15 | — | — | US | disclosed |
| US-4110472-A | CEREBROVASCULAR INSUFFICIENCY, PSYCHOSTIMULATION | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-29 | — | — | US | disclosed |
| US-4048100-A | Polyhalogenated polyols and foamed polyurethanes prepared from them | THE DOW CHEMICAL COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4036973-A | BACTERICIDES AND ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170275250-A1 | PIPERIDINE COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME AND ITS USE | PGC, VIP, PIGO | ALDH1A1 365/4885GLA 3931/4885TDP1 3850/4885 |
| US-10144709-B2 | Piperidine compounds, pharmaceutical composition comprising the same and its use | PGC, VIP, PIGO | ALDH1A1 365/4885GLA 3931/4885TDP1 3850/4885 |
| US-20190092727-A1 | Piperidine Compounds, Pharmaceutical Composition Comprising The Same And Its Use | PGC, VIP, PIGO | ALDH1A1 365/4885GLA 3931/4885TDP1 3850/4885 |
| US-20240166602-A1 | SUBSTITUTED DIARYL COMPOUND AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF | DLD, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DHODH | ALDH1A1 903/4885GLA 3800/4885TDP1 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.