Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962011 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL2338368 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL29847389 | 1.00 | ALDH1A1 (0.49) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL2230996 | 0.89 | TTR (0.45) | ALDH1A1GLATSHRTP53CYP3A4 | |
| SCHEMBL30161198 | 0.89 | TTR (0.45) | ALDH1A1GLATSHRTP53CYP3A4 | |
| SCHEMBL9840397 | 0.87 | KDM4E (0.44) | ALDH1A1GLATDP1TSHRSMN1; SMN2 | |
| SCHEMBL2337120 | 0.86 | ALDH1A1 (0.49) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL9803136 | 0.85 | ALDH1A1 (0.59) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL2122103 | 0.83 | ALDH1A1 (0.46) | ALDH1A1GLATDP1TSHRTP53 | |
| SCHEMBL4294711 | 0.83 | ALDH1A1 (0.46) | ALDH1A1GLATDP1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| WO-2000006082-A2 | TREATMENT OF ANXIETY DISORDERS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| WO-2000006166-A1 | 5-HT1F ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |