Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | USP10 | Q14694 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4034581 | 0.82 | ALDH1A1 (0.35) | ALDH1A1SLC10A6VCAM1MAPTNPC1 | |
| SCHEMBL3840101 | 0.79 | ERCC1 (0.39) | ALDH1A1ERCC1FEN1ERCC4ERN1 | |
| SCHEMBL4033473 | 0.78 | ERCC1 (0.60) | ERCC1FEN1ERCC4 | |
| SCHEMBL13646995 | 0.78 | KMT2A (0.45) | ALDH1A1ERCC1FEN1ERCC4MAPT | |
| SCHEMBL4028581 | 0.77 | ERCC1 (0.44) | ALDH1A1ERCC1FEN1ERCC4SLC10A6 | |
| SCHEMBL13647162 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL3833902 | 0.73 | ERCC1 (0.60) | ALDH1A1ERCC1FEN1ERCC4MAPT | |
| SCHEMBL1848834 | 0.70 | ALDH1A1 (0.60) | ALDH1A1SLC10A6MAPTNPC1RAB9A | |
| SCHEMBL13647186 | 0.69 | GAA (0.42) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL23467921 | 0.69 | ERCC1 (0.56) | ALDH1A1ERCC1FEN1ERCC4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309566-B1 | DIHYDROXYPYRIMIDINE CARBOXYLIC ACIDS AS VIRAL POLYMERASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-10-07 | — | — | EP | disclosed |