Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27470508 | 0.85 | KMT2A (0.57) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| SCHEMBL8268852 | 0.83 | KMT2A (0.56) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| SCHEMBL29499086 | 0.81 | MEN1 (0.49) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| SCHEMBL6444461 | 0.81 | KMT2A (0.53) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL4786867 | 0.80 | HDAC8 (0.61) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| SCHEMBL6930590 | 0.80 | HDAC8 (0.56) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| SCHEMBL6477827 | 0.80 | HDAC8 (0.56) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| SCHEMBL2791174 | 0.80 | HDAC8 (0.56) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| SCHEMBL288272 | 0.79 | GAA (0.58) | KMT2AMEN1OPRM1OPRD1OPRK1 | |
| SCHEMBL288260 | 0.79 | GAA (0.58) | KMT2AMEN1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309566-B1 | DIHYDROXYPYRIMIDINE CARBOXYLIC ACIDS AS VIRAL POLYMERASE INHIBITORS | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-10-07 | — | — | EP | disclosed |