Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.56 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.55 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.55 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3971039 | 0.99 | ALDH1A1 (0.63) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL13648890 | 0.99 | ALDH1A1 (0.67) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| Hydrochloric Acid SCHEMBL3977312 | 0.97 | ALDH1A1 (0.65) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL3975118 | 0.95 | ALDH1A1 (0.65) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| Hydrochloric Acid SCHEMBL3972227 | 0.94 | ALDH1A1 (0.64) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL1744106 | 0.89 | ALDH1A1 (0.55) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL4433768 | 0.88 | ADRA1A (0.57) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL4140037 | 0.87 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL4130774 | 0.87 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBHPGDALOX15 | |
| SCHEMBL13648886 | 0.87 | HDAC1 (0.61) | ALDH1A1KDM4EPOLBHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264435-A1 | Novel Aryl- and Heteroarylpiperazines | HIGH POINT PHARMACEUTICALS, LLC (US) | 2009-10-22 | — | — | US | disclosed |
| US-20090264435-A1 | Novel Aryl- and Heteroarylpiperazines | HIGH POINT PHARMACEUTICALS, LLC (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264435-A1 | Novel Aryl- and Heteroarylpiperazines | HRH3, HRH2, HRH4 | ALDH1A1 2719/4885KDM4E 1574/4885POLB 4110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.