SCHEMBL13649261

SCHEMBL13649261

Cc1ccccc1N(C)S(=O)(=O)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 1/20 0.65
CA12 O43570 1/20 0.53
CA9 Q16790 1/20 0.53
GAA P10253 2/20 0.50
TEAD1 P28347 1/20 0.48
LMNA P02545 1/20 0.48
TSHR P16473 1/20 0.48
NR1I2 O75469 1/20 0.46
KEAP1 Q14145 1/20 0.46
HTR6 P50406 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
APOBEC3G Q9HC16 1/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
HSD11B1 P28845 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7150548 0.89 C5AR1 (0.83) C5AR1CA12CA9GAALMNA
SCHEMBL15756100 0.86 C5AR1 (0.62) C5AR1CA12CA9LMNATSHR
SCHEMBL17174226 0.86 C5AR1 (0.62) C5AR1CA12CA9LMNATSHR
SCHEMBL17174236 0.86 C5AR1 (0.62) C5AR1CA12CA9GAALMNA
SCHEMBL25920653 0.86 C5AR1 (0.62) C5AR1CA12CA9LMNATSHR
SCHEMBL17174232 0.83 KEAP1 (0.70) C5AR1LMNAKEAP1KMT2A
SCHEMBL5853978 0.82 TEAD1 (0.49) C5AR1CA12CA9TEAD1HTR6
SCHEMBL17174225 0.82 C5AR1 (0.57) C5AR1CA12CA9LMNATSHR
SCHEMBL17174229 0.82 C5AR1 (0.57) C5AR1CA12CA9LMNATSHR
SCHEMBL17174230 0.80 RAB9A (0.58) C5AR1LMNAHTR6NPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184520-A Biphenyl amine compound, preparation method thereof and application thereof in flow battery 中国科学院大连化学物理研究所 2024-06-14 CN claimed
EP-2838533-B1 COMPOSITIONS AND METHODS OF MODULATING 15-PGDH ACTIVITY UNIV CASE WESTERN RESERVE (US) 2017-10-04 EP disclosed
US-20150291517-A1 BENZENESULFONAMIDE COMPOUNDS FOR SOMATIC EMBRYOGENESIS IN PLANTS STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK (NL) 2015-10-15 US disclosed
US-20150291517-A1 BENZENESULFONAMIDE COMPOUNDS FOR SOMATIC EMBRYOGENESIS IN PLANTS STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK (NL) 2015-10-15 US disclosed
US-8502937-B2 Protective film for polarizers FUJIFILM CORPORATION (JP) 2013-08-06 US disclosed
US-8502937-B2 Protective film for polarizers FUJIFILM CORPORATION (JP) 2013-08-06 US disclosed
US-20090244705-A1 PROTECTIVE FILM FOR POLARIZERS FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090244705-A1 PROTECTIVE FILM FOR POLARIZERS FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
US-20090096963-A1 CYCLIC POLYOLEFIN FILM, PROCESS FOR PRODUCING THE FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-16 US disclosed
US-20090096963-A1 CYCLIC POLYOLEFIN FILM, PROCESS FOR PRODUCING THE FILM, AND POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2009-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291517-A1 BENZENESULFONAMIDE COMPOUNDS FOR SOMATIC EMBRYOGENESIS IN PLANTS KCNJ2, HCN2, HACL2 C5AR1 4657/4885CA12 3085/4885CA9 3523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.