SCHEMBL17174232

SCHEMBL17174232

COc1ccc(S(=O)(=O)N(C)c2ccccc2C)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 3/20 0.70
CYP2C9 P11712 1/20 0.60
PGR P06401 1/20 0.58
C5AR1 P21730 1/20 0.58
MMP9 P14780 2/20 0.55
MMP13 P45452 2/20 0.55
MMP2 P08253 1/20 0.55
MMP3 P08254 1/20 0.55
FFAR4 Q5NUL3 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.52
TUBB4A P04350 1/20 0.51
TUBB P07437 1/20 0.51
TUBA3C P0DPH7 1/20 0.51
STAT3 P40763 1/20 0.51
TUBA1B P68363 1/20 0.51
TUBA4A P68366 1/20 0.51
TUBB4B P68371 1/20 0.51
TUBB3 Q13509 1/20 0.51
TUBB2A Q13885 1/20 0.51
TUBB8 Q3ZCM7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7150548 0.83 C5AR1 (0.83) CYP2C9C5AR1MMP9MMP2L3MBTL1
SCHEMBL13649261 0.83 C5AR1 (0.65) KEAP1C5AR1KMT2ALMNA
SCHEMBL29782141 0.82 KEAP1 (0.81) KEAP1CYP2C9PGRC5AR1MMP9
SCHEMBL17174226 0.81 C5AR1 (0.62) KEAP1C5AR1MCOLN3KMT2ALMNA
SCHEMBL15756100 0.81 C5AR1 (0.62) KEAP1PGRC5AR1MMP9MMP13
SCHEMBL17174236 0.81 C5AR1 (0.62) KEAP1CYP2C9C5AR1L3MBTL1MCOLN3
SCHEMBL25920653 0.81 C5AR1 (0.62) KEAP1CYP2C9C5AR1MCOLN3LMNA
SCHEMBL7267305 0.79 PGR (0.82) KEAP1PGRL3MBTL1MCOLN3KMT2A
SCHEMBL17174230 0.78 RAB9A (0.58) C5AR1L3MBTL1POLBKMT2ALMNA
SCHEMBL17174225 0.77 C5AR1 (0.57) KEAP1C5AR1POLBMCOLN3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150291517-A1 BENZENESULFONAMIDE COMPOUNDS FOR SOMATIC EMBRYOGENESIS IN PLANTS STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK (NL) 2015-10-15 US disclosed
US-20150291517-A1 BENZENESULFONAMIDE COMPOUNDS FOR SOMATIC EMBRYOGENESIS IN PLANTS STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK (NL) 2015-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291517-A1 BENZENESULFONAMIDE COMPOUNDS FOR SOMATIC EMBRYOGENESIS IN PLANTS KCNJ2, HCN2, HACL2 KEAP1 2422/4885CYP2C9 2841/4885PGR 1936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.