Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12907902 | 0.92 | HTR1A (0.34) | HTR1AGPR119NAAAHCRTR2 | |
| SCHEMBL12836534 | 0.92 | PIM1 (0.30) | HTR1ANAAA | |
| SCHEMBL10303370 | 0.89 | HTR1A (0.31) | HTR1A | |
| SCHEMBL12223471 | 0.87 | HTR1A (0.33) | HTR1AHCRTR2 | |
| SCHEMBL13586197 | 0.87 | GPR119 (0.33) | HTR1AGPR119HCRTR2 | |
| SCHEMBL12907089 | 0.86 | HTR1A (0.35) | HTR1AHCRTR2KDM5AKDM4CKDM5B | |
| SCHEMBL11942597 | 0.84 | NAAA (0.34) | HTR1AGPR119NAAA | |
| SCHEMBL12836536 | 0.84 | PIM1 (0.33) | HTR1A | |
| SCHEMBL12836566 | 0.84 | PIM1 (0.33) | HTR1A | |
| SCHEMBL13654183 | 0.84 | HTR1A (0.34) | HTR1AHCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125668-A1 | TRICYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | チッソ株式会社 (JP) | 2009-10-15 | — | — | WO | disclosed |