Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 7/20 | 0.65 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.62 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30395319 | 1.00 | GPBAR1 (0.69) | GPBAR1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL29058683 | 0.89 | ALDH1A1 (0.82) | GPBAR1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL29058951 | 0.84 | GPBAR1 (0.78) | GPBAR1ALDH1A1LMNANPSR1TDP1 | |
| SCHEMBL12204335 | 0.81 | LMNA (0.79) | GPBAR1ALDH1A1LMNANPSR1TDP1 | |
| SCHEMBL8362479 | 0.79 | GPBAR1 (0.60) | GPBAR1ALDH1A1LMNATDP1USP2 | |
| SCHEMBL1309805 | 0.79 | GPBAR1 (0.60) | GPBAR1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL25754367 | 0.78 | GPBAR1 (0.70) | GPBAR1ALDH1A1LMNATDP1USP2 | |
| SCHEMBL5533828 | 0.78 | LMNA (0.74) | GPBAR1ALDH1A1LMNATSHRTDP1 | |
| SCHEMBL12204291 | 0.75 | LMNA (1.00) | GPBAR1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL30395450 | 0.75 | EPAS1 (1.00) | GPBAR1ALDH1A1LMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116236478-A | Application of aromatic heterocyclic formamide compound | 浙江大学 | 2023-06-09 | — | — | CN | disclosed |
| WO-2009123588-A1 | AMIDES OF 3, 5-SUBSTITUTED-IS0XAZ0LE-4-CARB0XYLIC ACIDS FOR THE TREATMENT OF VIRAL INFECTIONS, CANCER AND RESTENOSIS | THE CLEVELAND CLINIC FOUNDATION (US) | 2009-10-08 | — | — | WO | disclosed |