Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.70 |
| ▸ | GHSR | Q92847 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12204335 | 0.90 | LMNA (0.79) | GPBAR1LMNATDP1MEN1KMT2A | |
| SCHEMBL25754367 | 0.85 | GPBAR1 (0.70) | GPBAR1LMNATDP1MEN1KMT2A | |
| SCHEMBL8362479 | 0.84 | GPBAR1 (0.60) | GPBAR1LMNATDP1MEN1KMT2A | |
| SCHEMBL13654932 | 0.84 | GPBAR1 (0.69) | GPBAR1LMNATDP1MEN1KMT2A | |
| SCHEMBL30395319 | 0.84 | GPBAR1 (0.69) | GPBAR1LMNATDP1MEN1KMT2A | |
| SCHEMBL29058683 | 0.83 | ALDH1A1 (0.82) | GPBAR1LMNATDP1MEN1KMT2A | |
| SCHEMBL30395450 | 0.82 | EPAS1 (1.00) | GPBAR1LMNATDP1MEN1KMT2A | |
| SCHEMBL31546967 | 0.80 | MAPT (0.76) | GPBAR1LMNATDP1MEN1KMT2A | |
| SCHEMBL29058927 | 0.80 | EPAS1 (1.00) | GPBAR1LMNATDP1MEN1KMT2A | |
| SCHEMBL29058648 | 0.80 | EPAS1 (0.77) | GPBAR1LMNATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116236478-A | Application of aromatic heterocyclic formamide compound | 浙江大学 | 2023-06-09 | — | — | CN | disclosed |