Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13659496 | 0.93 | LMNA (0.43) | LMNAHPGDF7MEN1KMT2A | |
| SCHEMBL1095648 | 0.92 | LMNA (0.43) | LMNAHPGDACACBF7 | |
| SCHEMBL13655028 | 0.90 | LMNA (0.44) | LMNAHPGDKMT2A | |
| SCHEMBL13655030 | 0.90 | LMNA (0.43) | LMNAHPGDMEN1KMT2A | |
| SCHEMBL13655043 | 0.89 | ACACB (0.41) | LMNAACACB | |
| SCHEMBL13654999 | 0.88 | KDM4E (0.49) | LMNAHPGDACACB | |
| SCHEMBL13655031 | 0.87 | LMNA (0.41) | LMNAHPGD | |
| SCHEMBL13655042 | 0.85 | LMNA (0.39) | LMNAHPGD | |
| SCHEMBL1109371 | 0.84 | LMNA (0.45) | LMNAHPGDF7MEN1KMT2A | |
| SCHEMBL13655022 | 0.84 | KDM4E (0.38) | LMNAHPGDACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247506-A1 | Antibacterial agents | CHIRON CORPORATION | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247506-A1 | Antibacterial agents | MRPL21, SI, PGLS | LMNA 3397/4885HPGD 408/4885ACACB 3199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.