Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461859 | 0.91 | ALDH1A1 (0.42) | ALDH1A1POLBSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL13659701 | 0.91 | ALDH1A1 (0.45) | ALDH1A1POLBSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL460072 | 0.88 | ALDH1A1 (0.48) | ALDH1A1POLBSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL400493 | 0.86 | ALDH1A1 (0.42) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL437259 | 0.84 | ALDH1A1 (0.46) | ALDH1A1POLBSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL10285906 | 0.82 | ALDH1A1 (0.44) | ALDH1A1POLBSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL402870 | 0.82 | ALDH1A1 (0.48) | ALDH1A1POLBSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL1095970 | 0.79 | ALDH1A1 (0.46) | ALDH1A1POLBSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL460940 | 0.79 | MAPT (0.42) | — | |
| SCHEMBL1109170 | 0.79 | ALDH1A1 (0.50) | ALDH1A1POLBSMN1; SMN2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247506-A1 | Antibacterial agents | CHIRON CORPORATION | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247506-A1 | Antibacterial agents | MRPL21, SI, PGLS | ALDH1A1 782/4885POLB 640/4885SMN1; SMN2 2296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.