SCHEMBL13655229

SCHEMBL13655229

Nc1ncc(-c2ccc(-c3ccccc3)cc2)[nH]1

nearest known ligand 0.92

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MASP2 O00187 1/20 0.92
SCN2A Q99250 5/20 0.57
NPY5R Q15761 4/20 0.57
LTA4H P09960 1/20 0.56
HPGDS O60760 2/20 0.49
PDE10A Q9Y233 1/20 0.47
SCN9A Q15858 1/20 0.47
AOC3 Q16853 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL725351 0.96 MASP2 (1.00) MASP2SCN2ANPY5RLTA4HHPGDS
SCHEMBL4244858 0.84 MASP2 (0.71) MASP2SCN2ANPY5RLTA4HHPGDS
SCHEMBL4053949 0.83 MASP2 (0.70) MASP2SCN2ANPY5RLTA4HSCN9A
Hydrochloric Acid SCHEMBL4243690 0.83 MASP2 (0.69) MASP2SCN2ANPY5RLTA4HHPGDS
SCHEMBL10979 0.82 MASP2 (0.68) MASP2SCN2ANPY5RLTA4HSCN9A
Hydrochloric Acid SCHEMBL4061012 0.82 MASP2 (0.68) MASP2SCN2ANPY5RLTA4HSCN9A
Trifluoroacetic Acid SCHEMBL16566514 0.81 MASP2 (0.72) MASP2SCN2ANPY5RLTA4HHPGDS
SCHEMBL13665045 0.81 MASP2 (0.72) MASP2SCN2ANPY5RLTA4HHPGDS
SCHEMBL18130901 0.80 MASP2 (0.66) MASP2SCN2ANPY5RLTA4HSCN9A
SCHEMBL20169742 0.80 MASP2 (0.66) MASP2SCN2ANPY5RLTA4HHPGDS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090270475-A1 INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2009-10-29 US disclosed
WO-2009123753-A1 INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES NORTH CAROLINA STATE UNIVERSITY (US) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270475-A1 INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES TFPI, O60361, PGLS MASP2 774/4885SCN2A 3744/4885NPY5R 4189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.