Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 1.00 |
| ▸ | SCN2A | Q99250 | 5/20 | 0.61 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.61 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 3/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655229 | 0.96 | MASP2 (0.92) | MASP2SCN2ANPY5RLTA4HHPGDS | |
| Trifluoroacetic Acid SCHEMBL16566514 | 0.85 | MASP2 (0.72) | MASP2SCN2ANPY5RLTA4HHPGDS | |
| SCHEMBL13665045 | 0.84 | MASP2 (0.72) | MASP2SCN2ANPY5RLTA4HHPGDS | |
| SCHEMBL4244858 | 0.84 | MASP2 (0.71) | MASP2SCN2ANPY5RLTA4HHPGDS | |
| SCHEMBL4053949 | 0.83 | MASP2 (0.70) | MASP2SCN2ANPY5RLTA4HAOC3 | |
| Hydrochloric Acid SCHEMBL4243690 | 0.82 | MASP2 (0.69) | MASP2SCN2ANPY5RLTA4HHPGDS | |
| SCHEMBL2768364 | 0.81 | MASP2 (0.68) | MASP2SCN2ANPY5RLTA4HHPGDS | |
| SCHEMBL10979 | 0.81 | MASP2 (0.68) | MASP2SCN2ANPY5RLTA4HSCN9A | |
| Hydrochloric Acid SCHEMBL4061012 | 0.81 | MASP2 (0.68) | MASP2SCN2ANPY5RLTA4HAOC3 | |
| SCHEMBL4056971 | 0.80 | MASP2 (0.67) | MASP2SCN2ALTA4HRAB9ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270217-A1 | IMIDAZ0[1,2-A]PYRIMIDINE-5(1 H)-ONES HAVING A COVALENT WARHEAD AT THE 3-POSITION AS WRN INHIBITORS | INCYTE CORPORATION (US) | 2025-08-28 | — | — | US | disclosed |
| US-9975857-B2 | Inhibition of bacterial biofilms with imidazole-phenyl derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-05-22 | — | — | US | disclosed |
| CN-102917775-B | There is the PA membrane of the coating comprising polyalkylene oxide and imidazolium compounds | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-11-25 | — | — | CN | disclosed |
| EP-1932844-B1 | CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL | NIPPON SODA CO (JP) | 2015-09-02 | — | — | EP | disclosed |
| US-20150183746-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2015-07-02 | — | — | US | disclosed |
| US-20150183746-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2015-07-02 | — | — | US | disclosed |
| US-9005643-B2 | Inhibition of bacterial biofilms with imidazole-phenyl derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-04-14 | — | — | US | disclosed |
| US-9005643-B2 | Inhibition of bacterial biofilms with imidazole-phenyl derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-04-14 | — | — | US | disclosed |
| US-8646616-B2 | Composite membrane with coating comprising polyalkylene oxide and imidazol compounds | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-02-11 | — | — | US | disclosed |
| CN-102917775-A | Polyamide membrane with coating comprising polyalkylene oxide and imidazol compounds | DOW GLOBAL TECHNOLOGIES LLC | 2013-02-06 | — | — | CN | disclosed |
| US-20110284454-A1 | COMPOSITE MEMBRANE WITH COATING COMPRISING POLYALKYLENE OXIDE AND IMIDAZOL COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-24 | — | — | US | disclosed |
| US-7816387-B2 | β secretase inhibitor | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2010-10-19 | — | — | US | disclosed |
| US-20090270475-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-29 | — | — | US | disclosed |
| US-20090270475-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-29 | — | — | US | disclosed |
| US-20090198056-A1 | Beta secretase inhibitor | KISO, YOSHIAKI (JP) | 2009-08-06 | — | — | US | disclosed |
| EP-1947098-A1 | CYCLIC AMINE COMPOUNDS AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2008-07-23 | — | — | EP | disclosed |
| EP-1942101-A1 | SECRETASE INHIBITOR | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2008-07-09 | — | — | EP | disclosed |
| WO-2008075109-A1 | SUBSTITUTED PIPERIDINES HAVING PROTEIN KINASE INHIBITING ACTIVITY | ASTEX THERAPEUTICS LIMITED (GB) | 2008-06-26 | — | — | WO | disclosed |
| EP-1932844-A1 | BRIDGED CYCLIC AMINE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2008-06-18 | — | — | EP | disclosed |
| WO-2000006552-A1 | 4-PHENYL- AND 4,5-DIPHENYLIMIDAZOLE DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION | SANOFI-SYNTHELABO (FR) | 2000-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090198056-A1 | Beta secretase inhibitor | BACE1, BACE2, APP | MASP2 1810/4885SCN2A 577/4885NPY5R 1400/4885 |
| US-20250270217-A1 | IMIDAZ0[1,2-A]PYRIMIDINE-5(1 H)-ONES HAVING A COVALENT WARHEAD AT THE 3-POSITION AS WRN INHIBITORS | WRN, RECQL, BLM | MASP2 3025/4885SCN2A 4344/4885NPY5R 4737/4885 |
| US-20090270475-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | TFPI, O60361, PGLS | MASP2 774/4885SCN2A 3744/4885NPY5R 4189/4885 |
| US-20150183746-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | TFPI, O60361, PGLS | MASP2 774/4885SCN2A 3744/4885NPY5R 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.