Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11597144 | 0.81 | PPARG (0.48) | PPARGSLC22A12KDM4EMAPTLMNA | |
| SCHEMBL11570463 | 0.80 | KDM4E (0.50) | PPARGKDM4EATMMAPTLMNA | |
| SCHEMBL11272764 | 0.77 | PPARG (0.51) | PPARGSLC22A12CNR2P2RY1CYP11B1 | |
| SCHEMBL13655381 | 0.77 | PPARG (0.43) | PPARGSLC22A12MAPTLMNAHTT | |
| SCHEMBL10566944 | 0.73 | KDM4E (0.48) | PPARGKDM4ECYP1A2CYP2C19ATM | |
| SCHEMBL3372794 | 0.73 | PPARG (0.51) | PPARGKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2450141 | 0.72 | PPARG (0.81) | PPARGSLC22A12CNR2P2RY1KDM4E | |
| SCHEMBL12189841 | 0.72 | PPARG (0.81) | PPARGSLC22A12CNR2P2RY1KDM4E | |
| SCHEMBL11596698 | 0.72 | PKM (0.45) | PPARGSLC22A12CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4779899 | 0.72 | KDM4E (0.50) | PPARGKDM4EATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8784774-B2 | Labeled molecular imaging agents and methods of use | GENERAL ELECTRIC COMPANY (US) | 2014-07-22 | — | — | US | disclosed |
| WO-2009121940-A1 | PROCESS FOR THE PREPARATION OF (-)-(4-CHLORO-PHENYL)-(3-TRIFLUOROMETHYL-PHENOXY)-ACETIC ACID 2-ACETYLAMINO-ETHYL ESTER | JANSSEN PHARMACEUTICA NV (BE) | 2009-10-08 | — | — | WO | disclosed |