Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3299127 | 0.82 | PPARG (0.60) | PPARGMEN1KMT2ADPP4DPP7 | |
| SCHEMBL12189840 | 0.82 | PPARG (0.60) | PPARGMEN1KMT2ADPP4DPP7 | |
| SCHEMBL3299123 | 0.82 | PPARG (0.60) | PPARGMEN1KMT2ADPP4DPP7 | |
| SCHEMBL3299728 | 0.82 | PPARG (0.60) | PPARGMEN1KMT2ADPP4DPP7 | |
| SCHEMBL13324898 | 0.77 | PPARG (0.62) | PPARGMEN1KMT2ALMNAHTT | |
| SCHEMBL13359395 | 0.77 | PPARG (0.62) | PPARGMEN1KMT2ALMNAHTT | |
| SCHEMBL13655312 | 0.77 | PPARG (0.53) | PPARGLMNAHTTMAPTHPGD | |
| SCHEMBL12097949 | 0.76 | ALDH1A1 (0.51) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL12097951 | 0.76 | ALDH1A1 (0.51) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL16502054 | 0.74 | PPARG (0.57) | PPARGMEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009121940-A1 | PROCESS FOR THE PREPARATION OF (-)-(4-CHLORO-PHENYL)-(3-TRIFLUOROMETHYL-PHENOXY)-ACETIC ACID 2-ACETYLAMINO-ETHYL ESTER | JANSSEN PHARMACEUTICA NV (BE) | 2009-10-08 | — | — | WO | disclosed |