Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372794 | 0.86 | PPARG (0.51) | KDM4EPPARGATMMAPTCES2 | |
| SCHEMBL10566944 | 0.86 | KDM4E (0.48) | KDM4EPPARGATMMAPTCES2 | |
| SCHEMBL4779899 | 0.84 | KDM4E (0.50) | KDM4EPPARGATMMAPTCES2 | |
| SCHEMBL15545847 | 0.81 | CNR1 (0.46) | PPARGMAPTCES2PPARAMRGPRX4 | |
| SCHEMBL13655312 | 0.80 | PPARG (0.53) | KDM4EPPARGATMMAPTLMNA | |
| SCHEMBL11570378 | 0.79 | LMNA (0.51) | PPARGMAPTPPARALMNAPOLB | |
| SCHEMBL9588829 | 0.79 | HSD11B1 (0.49) | KDM4EPPARGMAPTPPARAPOLB | |
| SCHEMBL14269947 | 0.79 | NPSR1 (0.49) | KDM4EPPARGMAPTPPARAMRGPRX4 | |
| SCHEMBL1871412 | 0.78 | CETP (0.45) | ATMMAPTLMNAPOLBALDH1A1 | |
| SCHEMBL2737127 | 0.78 | L3MBTL1 (0.47) | KDM4EPPARGATMMAPTCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151303-A | Phenoxyalkylcarboxylic acid compounds and serum-lipid and triglyceride depressing therapeutic compositions | BOEHRINGER MANNHEIM GMBH (DE) | 1979-04-24 | — | — | US | disclosed |