Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 17/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054860 | 0.88 | GABRG2 (0.44) | GABRG2GABRB3GABRA5NR1H2NR1H3 | |
| SCHEMBL4062460 | 0.82 | GABRG2 (0.45) | GABRG2GABRB3GABRA5NR1H2NR1H3 | |
| SCHEMBL4242529 | 0.80 | GABRG2 (0.38) | GABRG2GABRB3GABRA5NR1H2 | |
| SCHEMBL24368122 | 0.79 | MAP4K4 (0.41) | NR1H2 | |
| SCHEMBL13655228 | 0.76 | KMT2A (0.42) | NR1H2NR1H3 | |
| SCHEMBL28645084 | 0.75 | ALDH1A1 (0.49) | — | |
| SCHEMBL13663124 | 0.75 | CNR2 (0.42) | NR1H2NR1H3 | |
| SCHEMBL4055209 | 0.75 | GABRG2 (0.43) | GABRG2GABRB3GABRA5NR1H2TTK | |
| SCHEMBL10117510 | 0.73 | MEN1 (0.45) | NR1H2 | |
| SCHEMBL10117536 | 0.72 | MTOR (0.38) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |