Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 8/20 | 0.35 |
| ▸ | NPC1 | O15118 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231082 | 0.87 | NR1H2 (0.41) | NR1H2CSNK2A2CSNK2A1GAARAB9A | |
| SCHEMBL4239515 | 0.87 | KDM4E (0.39) | NR1H2L3MBTL1GAARAB9ANPC1 | |
| SCHEMBL4054860 | 0.86 | GABRG2 (0.44) | GABRG2GABRB3GABRA5NR1H2 | |
| SCHEMBL4057543 | 0.85 | NR1H2 (0.36) | GABRG2GABRB3GABRA5NR1H2L3MBTL1 | |
| SCHEMBL4237042 | 0.85 | NR1H2 (0.38) | GABRG2GABRB3GABRA5NR1H2L3MBTL1 | |
| SCHEMBL4243989 | 0.84 | FFAR1 (0.36) | NR1H2L3MBTL1CSNK2A2CSNK2A1GAA | |
| SCHEMBL4238011 | 0.83 | NR1H2 (0.37) | GABRG2GABRB3GABRA5NR1H2L3MBTL1 | |
| SCHEMBL4237855 | 0.83 | NR1H2 (0.35) | GABRG2GABRB3GABRA5NR1H2L3MBTL1 | |
| SCHEMBL4057049 | 0.82 | RAB9A (0.38) | L3MBTL1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4241713 | 0.81 | FGFR3 (0.38) | NR1H2GAARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |