Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | CDK8 | P49336 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366781 | 0.85 | RAB9A (0.47) | KMT2ARAB9ASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL2231632 | 0.79 | ADORA1 (0.51) | KMT2ARAB9ASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL7749921 | 0.79 | ADORA1 (0.55) | KMT2ARAB9ASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL14274543 | 0.79 | ADORA1 (0.51) | KMT2ARAB9ASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL22587420 | 0.76 | ACP1 (0.64) | KMT2ARAB9ASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL22587412 | 0.76 | ABCG2 (0.62) | KMT2ASMN1; SMN2ALDH1A1POLBADORA1 | |
| SCHEMBL9983000 | 0.75 | SGK1 (0.55) | KMT2ARAB9ASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL5134352 | 0.74 | ADORA2A (0.44) | KMT2ARAB9ASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL6530422 | 0.72 | ADORA1 (0.47) | KMT2ARAB9ASMN1; SMN2ALDH1A1GLA | |
| SCHEMBL6529073 | 0.72 | ADORA1 (0.45) | KMT2ARAB9ASMN1; SMN2ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450811-B1 | Compounds specific to adenosine A1 and A3 receptors and uses thereof | OSI PHARM INC (US) | 2009-10-21 | — | — | EP | disclosed |
| EP-2050751-A1 | Compounds specific to adenosine A1 and A3 receptors and uses thereof | OSI Pharmaceuticals, Inc. (US) | 2009-04-22 | — | — | EP | disclosed |