Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 5/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 5/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 5/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13602802 | 0.90 | KMT2A (0.59) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL13121245 | 0.88 | CYP2C9 (0.62) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL13610022 | 0.71 | MEN1 (0.46) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL31563597 | 0.69 | LMNA (0.45) | KDM4EBRD4CREBBPPARP1LMNA | |
| SCHEMBL13610019 | 0.68 | KDM4E (0.56) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL13610542 | 0.67 | MEN1 (0.55) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL13602795 | 0.65 | MEN1 (1.00) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL5670399 | 0.65 | CA2 (0.62) | KDM4EKMT2ABRD4CREBBPPARP1 | |
| SCHEMBL13602810 | 0.64 | MEN1 (0.80) | MAPTKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL13602808 | 0.64 | MEN1 (0.80) | MAPTKDM4EMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346993-B1 | LACTAM COMPOUNDS AND MEDICAL USE THEREOF | AJINOMOTO KK (JP) | 2009-10-21 | — | — | EP | disclosed |