Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.35 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 4/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655513 | 0.90 | MAPT (0.48) | KMT2AMEN1KDM4EMAPTCYP1A2 | |
| SCHEMBL13121245 | 0.90 | CYP2C9 (0.62) | KMT2AMEN1KDM4EMAPTCYP1A2 | |
| SCHEMBL5670399 | 0.75 | CA2 (0.62) | KMT2AKDM4EBRD4CREBBPPARP1 | |
| SCHEMBL13602795 | 0.74 | MEN1 (1.00) | KMT2AMEN1KDM4EMAPTCYP1A2 | |
| SCHEMBL31563602 | 0.70 | BRD4 (0.37) | KMT2AMEN1KDM4EMAPTBRD4 | |
| SCHEMBL31563597 | 0.70 | LMNA (0.45) | KDM4EBRD4CREBBPPARP1AR | |
| SCHEMBL14267652 | 0.68 | MAPT (0.56) | KMT2AMEN1KDM4EMAPTCYP1A2 | |
| SCHEMBL5673003 | 0.68 | PARP1 (0.42) | KMT2AMEN1MAPTBRD4CREBBP | |
| SCHEMBL29044382 | 0.68 | MAPT (0.73) | KMT2AMEN1KDM4EMAPTCYP1A2 | |
| SCHEMBL13602815 | 0.68 | MEN1 (0.84) | KMT2AMEN1KDM4EMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632830-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2009-12-15 | — | — | US | disclosed |
| US-20080096862-A1 | LACTAM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | AJINOMOTO CO., INC. (JP) | 2008-04-24 | — | — | US | disclosed |
| US-7326701-B2 | Lactam compounds and pharmaceutical use thereof | AJINOMOTO CO., INC. (JP) | 2008-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096862-A1 | LACTAM COMPOUNDS AND PHARMACEUTICAL USE THEREOF | SLC2A4, SLC2A8, SLC2A1 | KMT2A 4672/4885MEN1 2372/4885KDM4E 3909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.