SCHEMBL13655514

SCHEMBL13655514

Cc1ccc(N(c2ccc(C)cc2)c2ccc(/C=N/N(c3ccccc3)c3cccc4ccccc34)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RRM1 P23921 2/20 0.40
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
ALDH1A1 P00352 4/20 0.37
MAPK1 P28482 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
MAPT P10636 2/20 0.37
LMNA P02545 1/20 0.37
SIGMAR1 Q99720 3/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
MCL1 Q07820 1/20 0.35
G6PC1 P35575 1/20 0.34
PSMD14 O00487 1/20 0.33
APAF1 O14727 1/20 0.33
USP2 O75604 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9775459 0.86 ALDH1A1 (0.49) RRM1MEN1KMT2AALDH1A1MAPK1
SCHEMBL9775460 0.86 ALDH1A1 (0.49) RRM1MEN1KMT2AALDH1A1MAPK1
SCHEMBL5921965 0.85 MAPT (0.46) MEN1KMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL5921967 0.85 MAPT (0.46) MEN1KMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL6260832 0.84 MAPT (0.48) MEN1KMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL12677649 0.84 MEN1 (0.48) MEN1KMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL1199116 0.84 MEN1 (0.48) MEN1KMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL359917 0.84 MEN1 (0.48) MEN1KMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL1199117 0.84 MEN1 (0.48) MEN1KMT2AALDH1A1MAPK1SMN1; SMN2
SCHEMBL1199348 0.84 MEN1 (0.48) MEN1KMT2AALDH1A1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090245867-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-01 US disclosed
US-20090245867-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2009-10-01 US disclosed