Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362269 | 0.86 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL13655586 | 0.86 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL3842943 | 0.86 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL13659592 | 0.81 | PTGS2 (0.72) | PTGS2 | |
| SCHEMBL6535135 | 0.73 | PTGS2 (0.60) | PTGS2 | |
| SCHEMBL6535146 | 0.72 | PTGS2 (0.44) | PTGS2KDM4E | |
| SCHEMBL7998603 | 0.68 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL13659627 | 0.65 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL7163192 | 0.65 | PTGS2 (0.61) | PTGS2 | |
| SCHEMBL13659631 | 0.65 | PTGS2 (0.48) | PTGS2KDM4EMEN1RECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090252678-A1 | COX-2-TARGETED IMAGING AGENTS | VANDERBILT UNIVERSITY (US) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090252678-A1 | COX-2-TARGETED IMAGING AGENTS | PTGS2, PTGES2, PTGER2 | PTGS2 1/4885KDM4E 4224/4885MEN1 2389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.