Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.72 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13659627 | 0.84 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL6535129 | 0.83 | PTGS2 (1.00) | PTGS2 | |
| SCHEMBL13655574 | 0.81 | PTGS2 (0.78) | PTGS2 | |
| SCHEMBL6535146 | 0.77 | PTGS2 (0.44) | PTGS2 | |
| SCHEMBL21101966 | 0.76 | PTGS2 (0.65) | PTGS2CYSLTR2CYSLTR1 | |
| SCHEMBL5316867 | 0.74 | PTGS2 (0.66) | PTGS2CYSLTR2CYSLTR1 | |
| SCHEMBL423421 | 0.74 | PTGS2 (0.66) | PTGS2 | |
| SCHEMBL18634033 | 0.73 | PTGS2 (0.54) | PTGS2CYSLTR2CYSLTR1 | |
| SCHEMBL25738358 | 0.72 | PTGS2 (0.55) | PTGS2CYSLTR2CYSLTR1 | |
| SCHEMBL7931176 | 0.72 | PTGS2 (0.63) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090252678-A1 | COX-2-TARGETED IMAGING AGENTS | VANDERBILT UNIVERSITY (US) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090252678-A1 | COX-2-TARGETED IMAGING AGENTS | PTGS2, PTGES2, PTGER2 | PTGS2 1/4885CYSLTR2 8/4885CYSLTR1 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.