Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13655913 | 0.89 | PPARA (0.40) | PPARGPPARASIGMAR1KMT2APOLB | |
| SCHEMBL4073429 | 0.88 | PPARA (0.60) | PPARGPPARA | |
| SCHEMBL13655823 | 0.88 | PPARA (0.50) | PPARGPPARASIGMAR1POLB | |
| SCHEMBL13655792 | 0.88 | PPARA (0.50) | PPARGPPARASIGMAR1POLB | |
| SCHEMBL4076444 | 0.85 | PPARA (0.49) | PPARGPPARAKMT2AFAAH | |
| Arginine SCHEMBL4076709 | 0.77 | PPARG (0.47) | PPARGPPARA | |
| Arginine SCHEMBL4073136 | 0.77 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL13656061 | 0.77 | SIGMAR1 (0.43) | PPARGPPARASIGMAR1POLB | |
| SCHEMBL13656062 | 0.77 | SLC2A1 (0.43) | SIGMAR1FAAH | |
| SCHEMBL4075627 | 0.76 | PPARA (0.69) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598293-B2 | Compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. (US) | 2009-10-06 | — | — | US | disclosed |