Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20079390 | 0.72 | JAK2 (0.35) | JAK2JAK3TSHR | |
| SCHEMBL14403679 | 0.68 | JAK2 (0.33) | JAK2JAK3 | |
| SCHEMBL12087744 | 0.62 | JAK2 (0.33) | JAK2JAK3 | |
| SCHEMBL602399 | 0.62 | CHRM2 (0.51) | JAK2JAK3 | |
| SCHEMBL13655800 | 0.61 | MAPK1 (0.31) | — | |
| SCHEMBL44492 | 0.61 | CHRM1 (0.63) | — | |
| SCHEMBL29467164 | 0.61 | CHRM1 (0.63) | — | |
| SCHEMBL1198100 | 0.60 | TNKS (0.53) | JAK2JAK3 | |
| SCHEMBL3243793 | 0.60 | HSD11B1 (0.53) | — | |
| SCHEMBL1760904 | 0.60 | OPRM1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3237403-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2020-05-06 | — | — | EP | disclosed |