SCHEMBL13655847

SCHEMBL13655847

O=CNC[C@H]1CN(c2ccc(N3CCN(C(=O)CO)CC3)c(F)c2)C(=O)O1

nearest known ligand 0.68

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 9/20 0.68
▸ MAOB P27338 10/20 0.59
▸ MAOA P21397 4/20 0.59
▸ LMNA P02545 1/20 0.58
▸ PTGS1 P23219 1/20 0.58
▸ CALML3 P27482 1/20 0.58
▸ SDHA P31040 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eperezolid SCHEMBL29421647 0.87 MAOB (0.76) F10MAOBMAOALMNAPTGS1
Eperezolid SCHEMBL186562 0.87 MAOB (0.76) F10MAOBMAOALMNAPTGS1
Eperezolid SCHEMBL1176950 0.87 MAOB (0.76) F10MAOBMAOALMNAPTGS1
SCHEMBL6160239 0.86 F10 (0.72) F10MAOBMAOALMNAPTGS1
SCHEMBL6160243 0.86 F10 (0.72) F10MAOBMAOALMNAPTGS1
Eperezolid SCHEMBL5325217 0.86 MAOB (0.75) F10MAOBMAOALMNAPTGS1
SCHEMBL6157003 0.85 F10 (0.71) F10MAOBMAOALMNAPTGS1
SCHEMBL6156993 0.85 F10 (0.71) F10MAOBMAOALMNAPTGS1
SCHEMBL14319697 0.85 F10 (0.71) F10MAOBMAOALMNAPTGS1
SCHEMBL6040334 0.85 F10 (0.70) F10MAOBMAOALMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090247545-A1 SUBSTITUTED OXAZOLIDINONE DERIVATIVES RANBAXY LABORATORIES LIMITED (IN) 2009-10-01 — — US disclosed
US-20090247545-A1 SUBSTITUTED OXAZOLIDINONE DERIVATIVES RANBAXY LABORATORIES LIMITED (IN) 2009-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247545-A1 SUBSTITUTED OXAZOLIDINONE DERIVATIVES OXA1L, MRPL21, ALPL F10 3268/4885MAOB 553/4885MAOA 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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